Viagra goes pink (finally!): First-of-its-kind cream promises to jump-start arousal in women

Viagra (sildenafil citrate) is in a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. These medications block the enzyme PDE5, which helps widen blood vessels to improve blood flow to the penis, making it easier to get and maintain an erection. When it was approved by the U.S. Food and Drug Administration (FDA) in 1998, sildenafil was the first oral medication available specifically for treating erectile dysfunction. You need a prescription to buy and use sildenafil. Sildenafil is pretty effective india viagra and safe when used correctly. But contrary to internet rumors, it’s only available as a pill — not as a gel. Some studies have looked at the possibility of using a sildenafil gel for erectile dysfunction. However, no manufacturers have actually pushed for it to be FDA-approved. Because of this, it’s currently not possible to buy a sildenafil-based ED gel in the U.S.

• The development of Viagra cream aims to improve convenience.
• It may allow for quicker libido response times.
• Compatibility with condom use varies; check labels.
• Some formulations are designed for extended release.
• Users with sensitive skin should opt for hypoallergenic versions.
• The safety profile of long-term topical use is not well-established.
• Dosage may be adjusted based on individual needs.
• Always follow storage and usage instructions carefully.
• Using too much can lead to unwanted side effects.
• Disclosure with a healthcare professional is recommended.

Many people seem to confuse sildenafil gel with sildenafil jelly, which is taken orally and isn’t available in the United States. (Well, not unless you get it from a dodgy online shop — which we don’t suggest.) It may also be confused with AndroGel® and alprostadil cream — more on these below. If you’re looking for a topical treatment for ED, Eroxon StimGel is a newer FDA-approved option. Made by the UK-based pharmaceutical company Futura Medical, it’s the first topical ED treatment legally available over the counter in the United States. But while some news outlets have dubbed Eroxon “topical Viagra,” the medication isn’t a PDE5 inhibitor like Viagra. Instead of blocking the PDE5 enzyme, this erectile dysfunction gel physically cools and warms the penis, according to the manufacturer’s website. This is thought to stimulate nerve endings and release nitric oxide to encourage better blood flow to the area. In a 12-week clinical trial of 250 men published on the manufacturer’s website, more than 60 percent saw improvement in ED symptoms, with some men getting erections within 10 minutes.

A fast-acting formula might sound appealing, given that Viagra takes around 30 minutes. However, there are some interesting factors to consider: Eroxon was the “placebo” in its first clinical trial. In the 12-week clinical trial, Eroxon was actually the “placebo.” The active drug consisted of nitroglycerin, a vasodilator. During the trial, researchers found that Eroxon (the placebo) performed almost as well as the active drug.

THE BIG “O” (OVERVIEW)

We source research from peer-reviewed medical journals, top government agencies, leading academic institutions, and respected advocacy groups. We also go beyond the research, interviewing top experts in their fields to bring you the most informed insights. Every article is rigorously reviewed by medical experts to ensure accuracy. Contact us at support@honehealth.com if you see an error. Be ready for sex whenever you're in the mood You may know it as the “little blue pill,” but have you heard of “Viagra gel” or “topical Viagra?” Scrolling through online forums for erectile dysfunction (ED), you may have seen discussions about a so-called sildenafil gel or sildenafil cream referring to the active ingredient in Viagra®, one of the most popular medications for ED.

Is topical sildenafil cream FDA-approved for women?

You massage these products onto the head of your penis and boom — you’re meant to get an erection soon after. Sildenafil isn’t available as a topical gel. One such product available over the counter (OTC) is Eroxon® StimGel, an ED gel inaccurately dubbed “topical Viagra.” Despite the moniker, Eroxon doesn’t contain sildenafil citrate — neither do any of the other erection gels and topicals commonly mislabeled as “Viagra gel.” While there are a few studies on OTC erectile dysfunction gels as potential treatments for ED, there’s currently not enough research to confirm they work as well as FDA-approved prescription ED drugs. If you’re one of the millions of men who experience erectile dysfunction, it’s good to know your options. Let’s talk about sildenafil gel for ED and other potential treatments. Eroxon was the “placebo” in its first clinical trial.

The FDA calls Eroxon a “non-medicated hydro-alcoholic gel.” It contains ethanol, carbomer, propylene, glycerine, and potassium hydroxide. These chemicals are found in various cosmetics and function as thickening agents, moisturizers, and lubricants. Other PDE5 inhibitors, specifically tadalafil, work better. In a second clinical trial comparing Eroxon (Med3000) to tadalafil (generic for Cialis), tadalafil showed a “greater improvement in erectile function.” Other PDE5 inhibitors, specifically tadalafil, work better. In a second clinical trial comparing Eroxon (Med3000) to tadalafil (generic for Cialis), tadalafil showed a “greater improvement in erectile function.” Some drug manufacturers make a version of sildenafil that’s sold as an oral jelly. This includes Kamagra Oral Jelly®, a flavored jelly from the Indian pharmaceutical company Ajanta Pharma. If swallowing a tablet is difficult for you, Kamagra may sound appealing. However, sildenafil jellies haven’t been approved by the FDA, and they aren’t legally available in the United States. The same goes for Osidea GL, another sildenafil gel from a Mexican manufacturer. Still, you might come across U.S.-based online stores selling Kamagra. They may market these products as supplements for sexual performance. To say this is a red flag is an understatement.

The Sexy Science Behind Dare to Play

Patience is essential for having a pleasurable experience with topical sildenafil. As the saying goes, everything comes (ahem) to she who waits. It can take up to 30 minutes for scream cream to absorb into your genital tissues. To get the most out of it, thoroughly massage the cream into your clitoris, labia, and surrounding tissues for 30 to 60 seconds. While you wait for the cream to do its magic, try other activities that support arousal, such as reading or listening to erotica, or snuggling with your partner.

Clinical ingredients made for women

And remember, there will be nights when you aren’t in the mood for sex—even after applying the cream—and that’s OK. While scream cream can be a powerful tool in your sexual toolbox, it’s not a wand-waving fairy godmother that makes all of your libido-blocking stressors disappear. If you have a pre-existing health condition, mention it to your doctor when you discuss scream cream, Snow says. Research shows the drug can increase the risk of severe arrhythmia (abnormal heartbeat) in people with cardiovascular disease (15). You should steer clear of sildenafil if you have a heart condition or recently had a stroke or heart attack, Snow adds. Selling Kamagra in the United States is illegal, for one thing, and there’s no way to tell if the products are real or fake. Kamagra is the most common imitation ED medication sold online, according to a 2010 review. The review also found that fake ED medications are often mislabeled and filled with contaminants — like talcum powder, commercial paint, and printer ink — as well as other dodgy ingredients. Basically, it’s not something you’d want in (or on) your body.

• Viagra cream might offer more control over dosing.
• It is often marketed to men seeking non-pill options.
• Some users report increased confidence with topical application.
• The cream is designed for convenience and discreetness.
• It may be combined with lubricants for comfort.
• Skin sensitivity varies, so patch testing is advised.
• The onset of action can be faster than oral forms.
• Interaction with other topical products is unknown.
• Not a cure for sexual dysfunction—only temporary enhancement.
• Consult a healthcare provider about underlying causes of ED.

Though these stores let you purchase ED medications without a prescription, buying from them is ill-advised. Sildenafil can be safe for many people, but it’s not suitable for everyone. For instance, it can be dangerous to use sildenafil if you’re also taking nitrates or hypertension (high blood pressure) medication.

• Viagra cream is considered experimental by many health authorities.
• It is not approved by the FDA for medical use.
• Efficacy evidence mainly comes from anecdotal reports.
• Risks associated include allergic reactions and skin burns.
• It can be part of a broader treatment plan for ED.
• Safe disposal of unused cream is necessary to prevent misuse.
• The cream may interact with other medications, demanding caution.
• Clinical trials are needed to confirm safety and efficiency.
• Patients should report adverse effects promptly.
• Distribution channels are often unregulated, so caution is advised.

This combination could lead to dangerously low blood pressure.

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Ditto if you have sickle cell anemia, hypotension, or liver issues (16). If you have a history of genital herpes, talk to your gynecologist before using scream cream. Research suggests taking high doses of L-arginine can increase the risk of a herpes breakout (17). Any time you start a new prescription drug or skincare product, be on the lookout for adverse effects, especially during your first couple of uses. “If you experience side effects such as skin irritation, rash, discomfort, headache, or discoloration after use, discontinue use,” Snow says.

Signalling mechanisms regulating lipolysis

If you use a scream cream containing testosterone, keep an eye out for acne, increased body hair, and changes in mood or personality, Berkheimer says. Scream cream and similar products are designed specifically for vulva owners. But these products are likely safe for non-op trans men, non-binary folks, and anyone else with a vulva. But scream cream isn’t made for cisgender men or other penis owners. If you have a penis, are navigating sexual dysfunction, and prefer topical products, talk to your doctor about other options like Eroxon (MED3000)—a recently FDA-approved, over-the-counter gel for erectile dysfunction (18). Although buying over-the-counter Viagra may sound convenient, landing in the hospital on date night is absolutely not. So pass on the Kamagra, and speak with a healthcare professional if you’re experiencing any form of sexual dysfunction. If a flavored treatment sounds good to you, consider Hims chewable ED mints.

• Viagra cream is a topical treatment designed for erectile dysfunction.
• It contains the active ingredient sildenafil.
• Applied directly to the skin for quick absorption.
• Typically used before sexual activity for increased blood flow.
• Often marketed as an alternative to oral tablets.
• May have fewer systemic side effects than pills.
• Application areas usually include the inner thigh or genitals.
• Effectiveness can vary depending on individual response.
• Needs to be applied about 15-30 minutes prior to sex.
• Not suitable for people allergic to sildenafil or similar drugs.

Some mixed up Viagra gel with AndroGel®, a topical gel prescribed to men with low testosterone levels.

Get a Personalized Treatment to Find Relief from Menopause.

Scream cream is a catch-all term for creams that boost sexual arousal. Sildenafil is usually the main active ingredient in scream cream, but it can also include testosterone or l-arginine. Topical sildenafil shows promise as a treatment for low desire, specifically those with female sexual arousal disorder. Since low libido is common during and after menopause, it could be a game changer for pleasure-seekers in peri- and post-menopause. You need a prescription for scream cream, so if you’re curious about trying it, talk to a sex-positive healthcare provider who specializes in menopause.

What is FSAD?

Current Regulatory Framework: Female Sexual Interest/Arousal Disorder (FSIAD). Safety and efficacy of sildenafil in postmenopausal women with sexual dysfunction. (210) Clitoral Blood Flow After Use of Gel Containing L-Arginine and L-Citrulline. Recurrent herpes zoster ophthalmicus in a young, healthy individual taking high doses of l-Arginine. The Edge upholds the highest standards of health journalism.

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